ProGsterol®

Product Highlights

• World’s First New Dietary Ingredient Deglusterol®
• Box of 30 Sachets | Unflavored Powder
• Blood Sugar Support for pre diabetes, Type II diabetes
• Revolutionary Diabetes Supplement
• Reverses Insulin Resistance for Pre-Diabetes & Type II Diabetes
• Reduces Blood Glucose Level in 30 minutes
• Supports Weight Loss
• Helps Lower Cholesterol
• Helps Reduce Triglyceride Levels
• Key Solution for Metabolic Syndrome
• FDA Approved | DRAP Approved |

Product Details

Country of Origin: Korea

Product Type: Dietary Supplement

Brand: ProGsterol

Ingredients: Deglusterol (Adiporin + Deobetide)

Quantity Per Pack: 30 sachet Pack

Specification: Box Container

Age: Adults

Dosage form: Powder

Manufacturer: Caregen

Packaging Dimensions: 14 x 11.1 x 9.5 cm; 156 g

Shipping: Free domestic shipping (3-5 business days)

Overview

ProGsterol is developed by the world’s leading peptides company, the biotech company Caregen (Republic of Korea) and successfully affects insulin resistance. Synthetic peptides are a progressive approach to the therapy of civilization.

Composition

ProGsterol’s composition contains a synthetic peptide Deglusterol, which increases the sensitivity of insulin receptors and affects cells with insulin resistance. Deglusterol is the world’s first synthetic peptide to be approved by the FDA (U.S. Food and Drug Administration) as a functional food supplement. Deglusterol consists of 2 peptides in a proportion of one to one: Adiporin (Adiporin) and Deobetide. Adiporin is a synthetic analogue of the human hormone Adiponectin. AMPK regulates metabolism in the cell, leads to balance. Deobetide suppresses and blocks the expression of TNF-alpha, which have an inflammatory effect. Peptides improve the body of people with type 2 diabetes.

FAQ's

What is ProGsterol?
• ProGsterol is a dietary supplement to maintain healthy blood glucose levels.
• ProGsterol enhances cell insulin sensitivity and glucose absorption to regulate blood sugar levels.
• ProGsterol was developed to reduce blood sugar levels and insulin resistance by improving insulin sensitivity at the cellular level, normalizing carbohydrate metabolism, and reducing inflammation.
What is ProGsterol made of?
• Main ingredient of ProGsterol is Deglusterol.
• Deglusterol is a synthetic peptide mixture made up of two peptides (Adiporin and Deobetide).
• Deglusterol breaks down into amino acids.
• These peptides consist of 5 and 9 amino acids respectively: alanine, arginine, asparagine, glycine, leucine, lysine, methionine, serine, and threonine. Each sachet contains 30 mg of Deglusterol.
What are peptides?

Peptides are short chains of amino acids (the building blocks of proteins), typically made up of 2 to 50 amino acids linked together. They play crucial roles in the body, acting as signaling molecules, hormones, and building blocks for various biological functions. For e.g.
• Hormone Regulation:
• Signaling and Communication
• Immune Support:
• Muscle Growth and Repair:
• Metabolic Regulation
• Anti-Inflammatory and Antioxidant Effects:

In supplements like ProGsterol, peptides are designed to target specific pathways or functions. The peptides in ProGsterol helps improve insulin sensitivity and reduce inflammation, supporting blood sugar management and metabolic health.

What is Deglusterol used for?

Deglusterol is used for treating insulin resistance-related diseases, including:
• Type II diabetes
• Pre-diabetes
• Obesity
• Metabolic dysfunction-associated steatotic liver disease (MASLD)
• Non-alcoholic fatty liver disease (NAFLD)
• Polycystic ovary syndrome (PCOS)

It helps improve insulin sensitivity, reduce inflammation, enhance glucose uptake, and promote lipid metabolism.

What is the mechanism of Deglusterol in reducing insulin resistance?
• Activation of the AMPK Pathway: Deglusterol activates the AMPK pathway, which plays a crucial role in enhancing insulin sensitivity and promoting glucose uptake in cells.
• Down-Regulation of Inflammation: It decreases the levels of inflammatory cytokines such as TNF-α, IL-1β, and other molecules that contribute to insulin resistance.
• Inhibition of Insulin Resistance Signals: Deglusterol reduces the phosphorylation of insulin resistance-related signaling molecules, which are typically elevated in the presence of inflammatory cytokines.
• Increase in Insulin Sensitivity Signals: It restores and increases the levels of insulin sensitivity molecules, including phospho-IRS (Tyr632), phospho-PI3K, phospho-AKT, and phospho-AMPK, which are essential for effective insulin signaling.
By addressing both inflammation and insulin signaling pathways, Deglusterol effectively reduces insulin resistance.
What is AMPK pathway?
In ProGsterol, AMPK (AMP-activated protein kinase) plays an essential role in enhancing insulin sensitivity and supporting metabolic health. Here’s how AMPK contributes:
1. Improves Insulin Sensitivity: By activating the AMPK pathway, ProGsterol helps cells respond better to insulin, which means glucose can be taken up more efficiently from the bloodstream and used for energy. This can help lower blood sugar levels and improve overall glucose metabolism.
2. Promotes Energy Balance: The activation of AMPK encourages the body to burn stored fat and use it for energy. This supports weight management and reduces fat buildup, including around the liver and organs.
3. Reduces Inflammation: AMPK activation can help reduce inflammation in the body by inhibiting inflammatory pathways. Since inflammation is often linked to insulin resistance, this action helps improve metabolic function.
4. Enhances Metabolic Pathways: ProGsterol’s effect on AMPK increases the expression of proteins involved in glucose uptake (like GLUT-4) and lipid metabolism, leading to better overall energy use and storage.
In summary, AMPK in ProGsterol helps to regulate energy use, reduce inflammation, and improve how the body handles insulin and blood sugar.
What is the Down-regulation of Inflammation means?
In ProGsterol, the down-regulation of inflammatory cytokines plays a crucial role in improving insulin sensitivity and supporting metabolic health. Here’s how it works:
1. Reducing Insulin Resistance: Inflammatory cytokines like TNF-α are known to interfere with insulin signaling, contributing to insulin resistance. By down-regulating these cytokines, ProGsterol helps improve how cells respond to insulin, enabling better glucose uptake and blood sugar control.
2. Lowering Chronic Inflammation: Chronic inflammation is linked to various metabolic disorders, including type 2 diabetes and fatty liver disease. ProGsterol’s ability to suppress the production and activity of inflammatory cytokines helps reduce inflammation throughout the body, supporting healthier metabolic function.
3. Supporting Weight Management: By reducing inflammation, ProGsterol helps regulate metabolic pathways that affect energy balance and fat storage. This can assist in weight management and prevent the buildup of excess fat, especially around vital organs.
4. Enhancing Overall Metabolic Health: By controlling inflammatory responses, ProGsterol helps create a more balanced metabolic environment. This not only supports better insulin action but also promotes improved lipid metabolism, aiding in cholesterol management and overall cardiovascular health.
In summary, the down-regulation of inflammatory cytokines in ProGsterol is vital for reducing inflammation, improving insulin response, and supporting healthy metabolism, making it beneficial for managing blood sugar levels and preventing metabolic issues.
What is the inhibition of insulin resistance signals means?
It refers to the process of blocking or reducing the biochemical pathways and signals that lead to insulin resistance in the body. Insulin resistance occurs when cells do not respond properly to insulin, resulting in impaired glucose uptake and higher blood sugar levels. This can lead to conditions such as type 2 diabetes and metabolic syndrome.
ProGsterol plays a key role in inhibiting insulin resistance signals by:
• Reducing Inflammatory Molecules: It lowers the activity of inflammation-related signaling molecules like TNF-α, JNK, and NF-kB, which are known to interfere with insulin signaling.
• Supporting Insulin Pathways: By blocking these disruptive signals, ProGsterol helps maintain the normal function of insulin signaling pathways, enhancing the body’s ability to manage blood sugar levels.
• Activating Beneficial Pathways: ProGsterol promotes pathways that improve insulin sensitivity, such as PI3K/AKT and AMPK, which support glucose uptake and energy regulation.
In essence, inhibition of insulin resistance signals helps improve how the body responds to insulin, reducing the risk of high blood sugar levels and associated metabolic disorders.
What do insulin sensitivity signals mean?
It refers to the biochemical pathways and signals that promote a positive response to insulin, allowing cells in the body to effectively absorb glucose from the bloodstream. When cells are sensitive to insulin, they can take up glucose efficiently, which helps maintain normal blood sugar levels and supports overall metabolic health.
ProGsterol enhances insulin sensitivity signals by:
• Activating Beneficial Pathways: It supports pathways like PI3K/AKT and AMPK that promote insulin sensitivity.
• Increasing Protein Expression: It boosts levels of important proteins like GLUT-4, which helps transport glucose into cells.
• Reducing Inflammation: By lowering inflammatory cytokines that interfere with insulin signaling, ProGsterol improves how cells respond to insulin.
In summary, insulin sensitivity signals are vital for effective glucose uptake and metabolic health, ensuring that the body uses insulin efficiently to maintain normal blood sugar levels.
What can ProGsterol do in my body in simple terms?
• It can reduce blood sugar levels (for pre-diabetics & type 2 diabetics)
• Reduce Insulin resistance which is the root cause of many health problems.
• It helps lose extra weight by avoiding sugar spikes in the body.
• Reduces Inflammation in the body.
• Improves Fatty liver disease (NAFLD)
• Enhances lipid metabolism, resulting in a decrease in triglycerides and cholesterol levels.
Who can take ProGsterol?
• Pre-diabetics and type II diabetics can take 1 stick per day.
• For weight loss, anyone can take 2 sticks per day. We recommend taking 1 stick before breakfast and 1 before dinner.
Does ProGsterol have any side effects?
• No side-effects. We have completed preclinical studies and human clinical trials to evaluate safety, and its efficacy and safety have been confirmed. Peptides are a combination of amino acids. Under the action of endogenous enzymes, they break down into simple amino acids, which are nutrients for the body and are safe for the body as a whole.
How to use ProGsterol?
• ProGsterol can be consumed by mixing a stick with a glass of water or any other drink.
Can you take ProGsterol alongside insulin and other medication?
• Yes, it is safe to take ProGsterol with your regular medications. However, you must check your reading and discuss with your doctor if your readings are improving.
Can I lose weight with ProGsterol?
• Yes, ProGsterol can be beneficial for weight loss when combined with a healthy diet and moderate physical activity.
Can ProGsterol help in reducing cholesterol?
Yes, ProGsterol helps in reducing cholesterol and triglycerides levels as part of its broader support for metabolic health. While ProGsterol’s primary focus is on improving insulin sensitivity and blood sugar control, its actions on AMPK activation, reduction of inflammation, and improved lipid metabolism can help in lowering cholesterol levels as part of a comprehensive approach to metabolic health.
Can children and pregnant women take ProGsterol?
• No tests have been conducted on children and pregnant women. Therefore, we cannot recommend ProGsterol for children and pregnant women.
Can I stop dieting and physical exercise with ProGsterol?
• Healthy eating and physical activity are always recommended for overall health. Therefore, while taking ProGsterol we do recommend eating healthy foods and some physical activity. However, if you crave sweets, we recommend taking ProGsterol before eating sweets.
Who else cannot take ProGsterol?
• People with type 1 diabetes.
• People with cancer and kidney disease.
How long should I take ProGsterol?
• Long-term use is recommended, but patients can decide how long to take based on their medical tests and their condition.
Should people take this product for life to be healthy?
• Long-term use is not a problem. The product is a key solution for metabolic health. It helps control triglyceride and cholesterol levels, reduce inflammation, improve fatty liver disease, reduce extra weight, help with hormonal issues like PCOS, and most importantly, reduce insulin resistance. The manufacturer recommends taking it for a long time. However, people can make decisions depending on their health status.
Is ProGsterol s drug? Do I need a prescription?
• No, ProGsterol is registered as a dietary supplement, as this will allow more people suffering from pre-diabetes and type 2 diabetes to take safe ProGsterol peptides easily. Deglusterol is the first synthetic peptide recognized by the US Food and Drug Administration as a functional food additive.